Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Pupil segmentation adaptive optics for in vivo mouse retinal fluorescence imaging

Not Accessible

Your library or personal account may give you access

Abstract

Adaptive Optics (AO) for scanning laser ophthalmoscopy enables high-resolution retinal imaging that can be used for preclinical research of diseases causing vision loss. Pupil Segmentation (PS) is an approach to wavefront-sensorless AO that acquires images within subregions across the imaging pupil to measure the wavefront slopes at the corresponding locations of the beam. We present PS-AO as an approach to correct ocular aberrations in 7s, implemented to minimize respiratory motion from an anesthetized mouse. We demonstrated an improvement in resolution and an image intensity increase of 25% across all results using PS-AO for in vivo fluorescence retinal imaging in mice using a MEMS-based segmented deformable mirror.

© 2017 Optical Society of America

Full Article  |  PDF Article
More Like This
Wavefront sensorless adaptive optics fluorescence biomicroscope for in vivo retinal imaging in mice

Daniel J. Wahl, Yifan Jian, Stefano Bonora, Robert J. Zawadzki, and Marinko V. Sarunic
Biomed. Opt. Express 7(1) 1-12 (2016)

Visible light sensorless adaptive optics for retinal structure and fluorescence imaging

Myeong Jin Ju, Christine Huang, Daniel J. Wahl, Yifan Jian, and Marinko V. Sarunic
Opt. Lett. 43(20) 5162-5165 (2018)

Adaptive optics in the mouse eye: wavefront sensing based vs. image-guided aberration correction

Daniel J. Wahl, Pengfei Zhang, Jacopo Mocci, Martino Quintavalla, Riccardo Muradore, Yifan Jian, Stefano Bonora, Marinko V. Sarunic, and Robert J. Zawadzki
Biomed. Opt. Express 10(9) 4757-4774 (2019)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Metrics

Select as filters


Select Topics Cancel
© Copyright 2022 | Optica Publishing Group. All Rights Reserved