Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Dual-view acoustic-resolution photoacoustic microscopy with enhanced resolution isotropy

Not Accessible

Your library or personal account may give you access

Abstract

Acoustic-resolution photoacoustic microscopy (AR-PAM) can provide penetration depths beyond the optical diffusion limit, but its lateral resolution is typically much worse than its axial resolution, resulting in a low-resolution isotropy. We herein present a dual-view AR-PAM (DV-AR-PAM) system that exploits two orthogonally arranged focused ultrasonic transducers. Taking advantage of their complementary acoustic detecting profiles, DV-AR-PAM allows the fusion of the dual-view signals, resulting in an enhancement in the resolution isotropy from 29% to 95% within one imaging plane, as demonstrated by simulation results on densely packed particles and experimental results on a single carbon fiber. The application of this method in vivo revealed distinct microvasculature structures in mouse skin that were previously indistinguishable with single-view detection, demonstrating the potential of DV-AR-PAM for vascular and neurological studies.

© 2018 Optical Society of America

Full Article  |  PDF Article
More Like This
Dual-view photoacoustic microscopy for quantitative cell nuclear imaging

De Cai, Terence T. W. Wong, Liren Zhu, Junhui Shi, Sung-Liang Chen, and Lihong V. Wang
Opt. Lett. 43(20) 4875-4878 (2018)

Isotropic-resolution photoacoustic microscopy with multi-angle illumination

Tianxiong Wang, Naidi Sun, Ruimin Chen, Qifa Zhou, and Song Hu
Opt. Lett. 44(1) 1-4 (2019)

Miniature probe for in vivo optical- and acoustic-resolution photoacoustic microscopy

Zhendong Guo, Yao Li, and Sung-Liang Chen
Opt. Lett. 43(5) 1119-1122 (2018)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Metrics

Select as filters


Select Topics Cancel
© Copyright 2022 | Optica Publishing Group. All Rights Reserved