Abstract

We propose, to the best of our knowledge, a new method to image fluorescent objects through turbid media based on Airy beam scanning. This is achieved by using the nondiffractive nature of Airy beams, namely their ability to maintain their shape while penetrating through a highly scattering medium. We show that our technique can image fluorescent objects immersed in turbid media with higher resolution and signal to noise than confocal imaging. As proof of principle, we demonstrate imaging of 1 μm sized fluorescent beads through a dense suspension of yeast cells with an attenuation coefficient of $51{\mathrm{cm}}^{-1}$ at a depth of 90 μm. Finally, we demonstrate that our technique can also provide the depth of the imaged object without any additional sectioning.

© 2019 Optical Society of America

Non-diffracting beams for label-free imaging through turbid media

Harel Nagar, Elad Dekel, Dror Kasimov, and Yael Roichman
Opt. Lett. 43(2) 190-193 (2018)

Volumetric two-photon microscopy with a non-diffracting Airy beam

Xiao-Jie Tan, Cihang Kong, Yu-Xuan Ren, Cora S. W. Lai, Kevin K. Tsia, and Kenneth K. Y. Wong
Opt. Lett. 44(2) 391-394 (2019)

Improve depth of field of optical coherence tomography using finite energy Airy beam

Miao Zhang, Zhijun Ren, and Ping Yu
Opt. Lett. 44(12) 3158-3161 (2019)

Depth-resolved volumetric two-photon microscopy based on dual Airy beam scanning

Hongsen He, Cihang Kong, Xiao-Jie Tan, Ka Yan Chan, Yu-Xuan Ren, Kevin K. Tsia, and Kenneth K. Y. Wong
Opt. Lett. 44(21) 5238-5241 (2019)

Image signal transmission with Airy beams

Yi Liang, Yi Hu, Daohong Song, Cibo Lou, Xinzheng Zhang, Zhigang Chen, and Jingjun Xu
Opt. Lett. 40(23) 5686-5689 (2015)