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Full-field passive elastography using digital holography

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Abstract

Off-axis digital holography is an imaging technique that allows direct measurement of phase and amplitude from one image. We utilize this technique to capture displacements induced by a diffuse shear wave field with high sensitivity. A noise-correlation-based algorithm is then used to measure mechanical properties of samples. This approach enables full-field quantitative passive elastography without the need of contact or a synchronized source of a mechanical wave. This passive elastography method is first validated on agarose test samples mimicking biological tissues, and first results on an ex vivo biological sample are presented.

© 2020 Optical Society of America

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