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Acoustic-resolution photoacoustic microscopy based on an optically transparent focused transducer with a high numerical aperture

Abstract

This Letter reports acoustic-resolution-photoacoustic microscopy (AR-PAM) based on a new optically transparent focused polyvinylidene fluoride (PVDF) transducer with a high acoustic numerical aperture (NA) of 0.64. Owing to the improved fabrication process, the new transducer has a much higher NA (0.64) than the previously reported low-NA transducer (${\rm{NA}} = {0.23}$). The acoustic center frequency and (pulse-echo) bandwidth are also increased to 36 and 44 MHz, respectively, which provides a 38 µm acoustic focal spot size and 210 µm acoustic depth of focus. For demonstration, AR-PAM was conducted on a twisted wire target in water and chicken breast tissue, and in vivo on a mouse tail. The imaging results show that high acoustic resolution and sensitivity can be achieved with a simple and compact setup to resolve the target at different depths. Such capabilities can be useful for the development of new AR-PAM systems for handheld, wearable, and even endoscopic imaging applications.

© 2021 Optical Society of America

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Corrections

Cheng Fang and Jun Zou, "Acoustic-resolution photoacoustic microscopy based on an optically transparent focused transducer with a high numerical aperture: erratum," Opt. Lett. 46, 3997-3997 (2021)
https://opg.optica.org/ol/abstract.cfm?uri=ol-46-16-3997

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Data Availability

Data underlying the results presented in this paper are not publicly available at this time but may be obtained from the authors upon reasonable request.

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