Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Scanning interferometric near-infrared spectroscopy

Not Accessible

Your library or personal account may give you access

Abstract

In diffuse optics, quantitative assessment of the human brain is confounded by the skull and scalp. To better understand these superficial tissues, we advance interferometric near-infrared spectroscopy (iNIRS) to form images of the human superficial forehead blood flow index (BFI). We present a null source–collector (S-C) polarization splitting approach that enables galvanometer scanning and eliminates unwanted backscattered light. Images show an order-of-magnitude heterogeneity in superficial dynamics, implying an order-of-magnitude heterogeneity in brain specificity, depending on forehead location. Along the time-of-flight dimension, autocorrelation decay rates support a three-layer model with increasing BFI from the skull to the scalp to the brain. By accurately characterizing superficial tissues, this approach can help improve specificity for the human brain.

© 2021 Optica Publishing Group

Full Article  |  PDF Article
More Like This
Reflectance-mode interferometric near-infrared spectroscopy quantifies brain absorption, scattering, and blood flow index in vivo

Dawid Borycki, Oybek Kholiqov, and Vivek J. Srinivasan
Opt. Lett. 42(3) 591-594 (2017)

Multi-exposure interferometric diffusing wave spectroscopy

Wenjun Zhou, Mingjun Zhao, Oybek Kholiqov, and Vivek J. Srinivasan
Opt. Lett. 46(18) 4498-4501 (2021)

Interferometric near-infrared spectroscopy (iNIRS): performance tradeoffs and optimization

Oybek Kholiqov, Dawid Borycki, and Vivek J. Srinivasan
Opt. Express 25(23) 28567-28589 (2017)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Supplementary Material (1)

NameDescription
Visualization 1       Movie of the time-of-flight-resolved field autocorrelation decay and light intensity from the human forehead.

Data availability

Data underlying the results presented in this paper may be obtained from the authors upon reasonable request.

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (5)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (6)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Metrics

Select as filters


Select Topics Cancel
© Copyright 2022 | Optica Publishing Group. All Rights Reserved