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Retinal blood flow imaging with combined full-field swept-source optical coherence tomography and laser Doppler holography

Léo Puyo, Hendrik Spahr, Clara Pfäffle, Gereon Hüttmann, and Dierck Hillmann

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Abstract

Full-field swept-source optical coherence tomography (FF-SS-OCT) and laser Doppler holography (LDH) are two holographic imaging techniques presenting unique capabilities for ophthalmology. We report on interlaced FF-SS-OCT and LDH imaging with a single instrument. Effectively, retinal blood flow and pulsation could be quasi-simultaneously monitored. This instrument holds potential for a wide scope of ophthalmic applications.

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Supplementary Material (4)

NameDescription
Visualization 1       In focus imaging with laser Doppler holography (LDH). Despite the intensity correction, there remains pixel-to-pixel differences in blood flow response that are clearly observed when the eye moves (the movie is registered).
Visualization 2       Defocus imaging with laser Doppler holography (LDH). The numerical wave propagation blurs the pixel-to-pixel differences in blood flow response.
Visualization 3       Dual measurement of retinal blood flow with laser Doppler holography (LDH) and holographic optical coherence tomography (OCT). Blood flow is measured in an artery and vein with LDH, and the changes in retinal thickness are monitored.
Visualization 4       Dual measurement of retinal blood flow with laser Doppler holography (LDH) and holographic optical coherence tomography (OCT). Blood flow is measured in an artery and vein with LDH, and the changes in retinal thickness are monitored.

Data availability

Data underlying the results presented in this paper are not publicly available at this time but may be obtained from the authors upon reasonable request.

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Figures (4)

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