Wide-field three-dimensional photoacoustic/ultrasound scanner using a two-dimensional matrix transducer array

Wangyu Kim; Wonseok Choi; Joongho Ahn; Changyeop Lee; Chulhong Kim

doi:10.1364/OL.475725

Optics Letters
Vol. 48,
Issue 2,
pp. 343-346
(2023)
•https://doi.org/10.1364/OL.475725

Wide-field three-dimensional photoacoustic/ultrasound scanner using a two-dimensional matrix transducer array

Wangyu Kim, Wonseok Choi, Joongho Ahn, Changyeop Lee, and Chulhong Kim

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Wangyu Kim, Wonseok Choi, Joongho Ahn, Changyeop Lee, and Chulhong Kim, "Wide-field three-dimensional photoacoustic/ultrasound scanner using a two-dimensional matrix transducer array," Opt. Lett. 48, 343-346 (2023)

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Abstract

Two-dimensional matrix transducer arrays are the most appropriate imaging probes for acquiring dual-modal 3D photoacoustic (PA)/ultrasound (US) images. However, they have small footprints which limit the field-of-view (FOV) to less than 10 mm × 10 mm and degrade the spatial resolution. In this study, we demonstrate a dual-modal PA and US imaging system (using a 2D matrix transducer array and a motorized 2D scanning system) to enlarge the FOV of volumetric images. Multiple PA volumes were merged to form a wide-field image of approximately 45 mm × 45 mm. In vivo imaging was demonstrated using rat sentinel lymph nodes (SLNs) and bladders stained with methylene blue. We believe that this volumetric PA/US imaging technique with a 2D matrix transducer array can be a useful tool for narrow-field real-time monitoring and wide-field imaging of various preclinical and clinical studies.

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Supplementary Material (2)

Name	Description
Visualization 1	Time-lapse photoacoustic maximum amplitude projection images of rat lymph node during methylene blue staining. Associated with Figure 3
Visualization 2	Volume rendered photoacoustic and ultrasound images of rat lymph nodes stained with methylene blue Associated with Figure 3

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Data underlying the results presented in this paper are not publicly available at this time but may be obtained from the authors upon reasonable request.

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