Abstract
All-optical ultrasound manipulates ultrasound waves based on laser and photonics technologies, providing an alternative approach for pulse-echo ultrasound imaging. However, its endoscopic imaging capability is limited ex vivo by the multifiber connection between the endoscopic probe and the console. Here, we report on all-optical ultrasound for in vivo endoscopic imaging using a rotational-scanning probe that relies on a small laser sensor to detect echo ultrasound waves. The acoustically induced lasing frequency change is measured via heterodyne detection by beating the two orthogonally polarized laser modes, enabling a stable output of ultrasonic responses and immunity to low-frequency thermal and mechanical disturbances. We miniaturize its optical driving and signal interrogation unit and synchronously rotate it with the imaging probe. This specialized design leaves a single-fiber connection to the proximal end and allows fast rotational scanning of the probe. As a result, we used a flexible, miniature all-optical ultrasound probe for in vivo rectal imaging with a B-scan rate of 1 Hz and a pullback range of ∼7 cm. This can visualize the gastrointestinal and extraluminal structures of a small animal. This imaging modality offers an imaging depth of 2 cm at a central frequency of ∼20 MHz, showing promise for high-frequency ultrasound imaging applications in gastroenterology and cardiology.
© 2023 Optica Publishing Group
Full Article | PDF ArticleMore Like This
Yan Li, Joseph Jing, Junxiao Yu, Buyun Zhang, Tiancheng Huo, Qiang Yang, and Zhongping Chen
Opt. Lett. 43(9) 2074-2077 (2018)
Peter H. Tran, David S. Mukai, Matthew Brenner, and Zhongping Chen
Opt. Lett. 29(11) 1236-1238 (2004)
Yujie Chen, Yan Wang, Tunan Lv, Junning Zhang, and Hongbin Yu
Opt. Lett. 48(4) 868-871 (2023)