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Spectral interference contrast based non-contact photoacoustic microscopy realized by SDOCT

Zhenhe Ma, Ning Ding, Zhen Li, Keliang Zhu, Ang Li, Zhanhong Lin, Yi Wang, Yuqian Zhao, Yao Yu, Jingmin Luan, Xin Zhu, and Jian Liu

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Abstract

We introduce a method to extract the photoacoustic (PA) signal from a contrast reduction of the interference spectrum acquired by spectral domain optical coherence tomography (SDOCT). This all-optical detection is achieved in a noncontact manner directly on the water surface covered on the sample by using its specular reflection. During SDOCT exposure, the phase of the interference spectrum keeps shaking according to the water surface vibration induced by PA excitation. This results in an interference contrast reduction which is quantified by a fast Fourier transform (FFT) for PA imaging. A tungsten filament, asparagus fern leaf, and mouse auricle are imaged to demonstrate the method.

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Supplementary Material (1)

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Supplement 1       Supplemental experiments

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Data underlying the results presented in this paper are not publicly available at this time but may be obtained from the authors upon reasonable request.

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