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Cardiac Sensing with Bio-Integrated Microlasers

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Abstract

The beating heart, characterized by ultrafast tissue dynamics and severe light scattering, is an exceptionally demanding environment even for advanced microscopy, yet characterizing the contraction of single cardiac cells is of fundamental importance in medicine. To overcome the limitations facing cardiac sensing, we explored the integration of microscopic lasers as novel, ultra-sensitive and remarkably bright probes of heart tissue’s contractility.

© 2020 Optical Society of America

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