The main principle is to detect ‘snake photons’ that, being predominantly forward scattered, retain more information about the sample. This is done practically by tilting the reference arm of the OCT setup allowing a spatio-angular filtering of light. In addition, speckle-resolved detection is used to increase significantly the signal-to-noise ratio through single-shot incoherent averaging. Finally, the combination of filtering and incoherent averaging results in the capability of imaging real tissues as deep as 4.5 mm with good axial and lateral resolution of about 0.4 mm. This work is the first proof-of-concept and further optimization, especially in the filtering procedure, can be achieved.
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