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Imaging collagen in a dermal equivalent using multi-photon microscopy

E. M. Gill, N. Ramanujam, C. A. Ivarie, J. M. Squirrell, and B. L. Allen-Hoffmann

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Abstract

Nondestructive imaging of tumor models offers a new tool for cancer research. We have imaged a dermal equivalent and measured a signal decrease using collagenase. This result indicates feasibility for measuring collagen degradation during tumorigenesis.

© 2004 Optical Society of America

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