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Conferences > BRAIN > 2023 > BM3B > BM3B.2

Next-generation head-mounted microscopes for large-scale neural recordings

Joseph R. Scherrer, Galen F. Lynch, Jie J. Zhang, and Michale S. Fee

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Abstract

We present a fluorescence microscope design that enables imaging of thousands of cortical neurons in freely-moving mice. The design eliminates traditional illumination optics, allowing for head-mounted microscopes with both a lower weight (1.4 gram) and a larger field-of-view (~4 mm diameter) than previously possible.

© 2023 The Author(s)

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