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Conferences > BRAIN > 2023 > BM4B > BM4B.2

Application of Machine Learning to Direct Calcium Indicator Engineering

Sarah J. Wait, Justin Daho Lee, Michael Rappleye, and Andre Berndt

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Abstract

Optimizing genetically encoded fluorescent indicators (GEFIs) is intellectually and experimentally taxing. We developed a machine learning (ML) platform to discover new variants of the calcium indicator GCaMP and illustrate ML’s ability to accelerate GEFI engineering.

© 2023 The Author(s)

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