Three-dimensional image-guided fluorescence using boundary element method and dual reciprocity method

Rong Yang; Subhadra Srinivasan; Robert L Scot Drysdale

doi:10.1364/ECBO.2011.80881U

Diffuse Optical Imaging III
Proceedings of SPIE-OSA Biomedical Optics (Optica Publishing Group, 2011),
paper 80881U
•https://doi.org/10.1364/ECBO.2011.80881U

Three-dimensional image-guided fluorescence using boundary element method and dual reciprocity method

Rong Yang, Subhadra Srinivasan, and Robert L Scot Drysdale

European Conference on Biomedical Optics 2011

Munich Germany
22–26 May 2011
ISBN: 9780819486851

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R. Yang, S. Srinivasan, and R. L. S. Drysdale, "Three-dimensional image-guided fluorescence using boundary element method and dual reciprocity method," in Diffuse Optical Imaging III, A. Hielscher and P. Taroni, eds., Vol. 8088 of Proceedings of SPIE-OSA Biomedical Optics (Optica Publishing Group, 2011), paper 80881U.

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Abstract

A boundary element method with dual reciprocity method (BEM-DRM) was used to model fluorescence in tissue using coupled diffusion equations in 3D. This method eliminates the need for node connectivity in a volume mesh of arbitrary shapes, requiring instead, a surface mesh with interior points to model the fluorescence source in 3D. Results using BEM-DRM show agreement with data from open source finite-element based software package NIRFAST⁷ with mean error difference of 0.08 for optimally chosen support parameter for radial basis functions used.

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