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  • Frontiers in Optics 2009/Laser Science XXV/Fall 2009 OSA Optics & Photonics Technical Digest
  • OSA Technical Digest (CD) (Optica Publishing Group, 2009),
  • paper JWC68
  • •https://doi.org/10.1364/FIO.2009.JWC68

Fluorescence Immunoassay for the Detection of Latent Tuberculosis Antigens with Single Molecule Sensitivity

Barbara S. Smith, Michael S. Scherman, Aubrey V. Weigel, Kristen L. Jevsevar, Jarvis W. Hill, John S. Spencer, Michael R. McNeil, and Diego Krapf

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Abstract

The successful identification and detection at the single molecule level of Antigen 85b, an antigen released by tuberculosis, was accomplished using a fluorescence-based immunoassay. This work enables a method for the diagnosis of latent tuberculosis.

© 2009 Optical Society of America

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