Tertiary structural effects on protein picosecond dynamics: terahertz dielectric response

Joseph R. Knab; Yunfen He; Ferdinand Lipps; Jing Yin Chen; Benjamin Moeller; Susan Gregurick; Andrea G. Markelz

doi:10.1364/LS.2007.LThC2

Frontiers in Optics 2007/Laser Science XXIII/Organic Materials and Devices for Displays and Energy Conversion
OSA Technical Digest (CD) (Optica Publishing Group, 2007),
paper LThC2
•https://doi.org/10.1364/LS.2007.LThC2

Tertiary structural effects on protein picosecond dynamics: terahertz dielectric response

Joseph R. Knab, Yunfen He, Ferdinand Lipps, Jing Yin Chen, Benjamin Moeller, Susan Gregurick, and Andrea G. Markelz

Laser Science 2007

San Jose, California United States
16–20 September 2007
ISBN: 1-55752-846-2

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Terahertz Spectroscopy I (LThC)

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J. R. Knab, Y. He, F. Lipps, J. Y. Chen, B. Moeller, S. Gregurick, and A. G. Markelz, "Tertiary structural effects on protein picosecond dynamics: terahertz dielectric response," in Frontiers in Optics 2007/Laser Science XXIII/Organic Materials and Devices for Displays and Energy Conversion, OSA Technical Digest (CD) (Optica Publishing Group, 2007), paper LThC2.

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Abstract

Terahertz time domain spectroscopy reveals hydration and temperature dependent “dynamical transitions” in both native and denatured proteins. These transitions may arise from hydration dependent side chain motion with these picosecond transitions subsequently influencing tertiary dynamics.

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