Abstract
We present advances in multiphoton and coherent Raman imaging for gastrointestinal cancer detection. We use stimulated Raman scattering (SRS) combined with second harmonic generation (SHG) to reveal cell nuclei, cytoplasm and collagen simultaneously in human tissues. For the first time cell nuclei, cytoplasm and extra cellular matrix can be visualized in real time with image quality similar to histology.
© 2017 Optical Society of America
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