Abstract
We developed and fabricated a preclinical photoacoustic imaging endoscope (PAIE) with an acousto-optic coaxial structure for cavity imaging that integrates a Plexiglas tube, an optical fiber, a ring transducer array, a taper reflector, and an ultrasonic coupling medium. A photoacoustic image for a section of pig colorectal tissue embedded in a transparent gelatin phantom was reconstructed. Furthermore, human colorectal cancer and normal colorectal tissue were imaged ex vivo with a contrast ratio of ~2.3. Experimental results demonstrate that the PAIE has potential for detecting colorectal cancer in clinical use.
© 2010 Optical Society of America
Full Article | PDF ArticleMore Like This
Chiye Li, Joon-Mo Yang, Ruimin Chen, Cheng-Hung Yeh, Liren Zhu, Konstantin Maslov, Qifa Zhou, K. Kirk Shung, and Lihong V. Wang
Opt. Lett. 39(6) 1473-1476 (2014)
Mucong Li, Chengbo Liu, Xiaojing Gong, Rongqin Zheng, Yuanyuan Bai, Muyue Xing, Xuemin Du, Xiaoyang Liu, Jing Zeng, Riqiang Lin, Huichao Zhou, Shouju Wang, Guangming Lu, Wen Zhu, Chihua Fang, and Liang Song
Biomed. Opt. Express 9(4) 1408-1422 (2018)
Xiandong Leng, William Chapman, Bin Rao, Sreyankar Nandy, Ruimin Chen, Rehan Rais, Ivan Gonzalez, Qifa Zhou, Deyali Chatterjee, Matthew Mutch, and Quing Zhu
Biomed. Opt. Express 9(11) 5159-5172 (2018)