Abstract
In this Letter, we present a photoacoustic imaging (PAI) system based on a low-cost high-power miniature light emitting diode (LED) that is capable of in vivo mapping vasculature networks in biological tissue. Overdriving with 200 ns pulses and operating at a repetition rate of 40 kHz, a 1.2 W 405 nm LED with a radiation area of and a size of was used to excite photoacoustic signals in tissue. Phantoms including black stripes, lead, and hair were used to validate the system in which a volumetric PAI image was obtained by scanning the transducer and the light beam in a two-dimensional x–y plane over the object. In vivo imaging of the vasculature of a mouse ear shows that LED-based PAI could have great potential for label-free biomedical imaging applications where the use of bulky and expensive pulsed lasers is impractical.
© 2017 Optical Society of America
Full Article | PDF ArticleMore Like This
Sandeep Kumar Kalva, Paul Kumar Upputuri, and Manojit Pramanik
Opt. Lett. 44(1) 81-84 (2019)
Heng Guo, Chaolong Song, Huikai Xie, and Lei Xi
Opt. Lett. 42(22) 4615-4618 (2017)
Xianjin Dai, Lei Xi, Can Duan, Hao Yang, Huikai Xie, and Huabei Jiang
Opt. Lett. 40(12) 2921-2924 (2015)