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Novel Optical Signature for Sickle Cell Trait Red Blood Cells

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Abstract

We identified unique optical signatures for sickle cell trait, a condition where heterozygous individuals are carriers for the hemoglobin allele that causes sickle cell anemia, by using wide-field interferometric microscopy.

© 2012 Optical Society of America

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More Like This
Relative Deformability of Red Blood Cells in Sickle Cell Trait and Sickle Cell Anemia by Trapping and Dragging

Rance Solomon, James Cooper, Gabriel Welker, Elaura Aguilar, Brooke Flanagan, Chelsey Pennycuff, David Scott, Anthony Farone, Mary Farone, Daniel Erenso, Robert Mushi, and Maria del Pilar Aguinaga
880307 European Conference on Biomedical Optics (ECBO) 2013

Heterozygotes and Homozygotes Genotypes Human Red Blood Cells Response to Trap and Drag Force

D. Erenso, R. Solomon, J. Cooper, G. Welker, E. Aguilar, B. Flanagan, C. Pennycuff, D. Scott, A. Farone, M. Farone, S. Mushi, and M.d.P. Aguinaga
JT2A.25 Bio-Optics: Design and Application (BODA) 2013

Response to Optical Trapping by Red Blood Cells (RBCs) from a Transfused Sickle Cell Patient

D. Erenso, A. Pellizzaro, G. Welker, O. Mohammed, A. Farone, M. Farone, and M.d.P. Aguinaga
BSu3A.38 Biomedical Optics (BIOMED) 2012

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