In Vivo Imaging of Neuronal Activity and Blood Vessels in AAV-Injected Mice

Anaïs Parrot; Anaïs Parrot; Jérémie Guilbert; Jérémie Guilbert; Pierre Girard-Collins; Pierre Girard-Collins; Michèle Desjardins; Michèle Desjardins

doi:10.1364/BRAIN.2023.BM4B.5

Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)
Technical Digest Series (Optica Publishing Group, 2023),
paper BM4B.5
•https://doi.org/10.1364/BRAIN.2023.BM4B.5

In Vivo Imaging of Neuronal Activity and Blood Vessels in AAV-Injected Mice

Anaïs Parrot, Jérémie Guilbert, Pierre Girard-Collins, and Michèle Desjardins

Optics and the Brain 2023

Vancouver, British Columbia Canada
24–27 April 2023
ISBN: 978-1-957171-21-0

From the session
Fluorescent Probes and Optogenetics I: Engineering and Applications (BM4B)

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A. Parrot, J. Guilbert, P. Girard-Collins, and M. Desjardins, "In Vivo Imaging of Neuronal Activity and Blood Vessels in AAV-Injected Mice," in Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN), Technical Digest Series (Optica Publishing Group, 2023), paper BM4B.5.

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Abstract

Characterizing neurovascular coupling helps to understand neurodegenerative diseases. Here, neuronal activity and vasculature were simultaneously measured in AAV-injected mice through transcranial windows by two-photon microscopy indicating strongly correlated signals synchronized with whiskers stimulations.

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