Visualizing drug actions on dendrites: psilocybin and other classic psychedelics

Ling-Xiao Shao; Clara Liao; Ian Gregg; Pasha A Davoudian; Pasha A Davoudian; Neil K Savalia; Neil K Savalia; Kristina Delagarza; Alex C. Kwan; Alex C. Kwan; Alex C. Kwan; Alex C. Kwan

doi:10.1364/BRAIN.2023.BTu2B.2

Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)
Technical Digest Series (Optica Publishing Group, 2023),
paper BTu2B.2
•https://doi.org/10.1364/BRAIN.2023.BTu2B.2

Visualizing drug actions on dendrites: psilocybin and other classic psychedelics

Ling-Xiao Shao, Clara Liao, Ian Gregg, Pasha A Davoudian, Neil K Savalia, Kristina Delagarza, and Alex C. Kwan

Optics and the Brain 2023

Vancouver, British Columbia Canada
24–27 April 2023
ISBN: 978-1-957171-21-0

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Fluorescent Probes and Optogenetics II: Engineering and Applications (BTu2B)

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L. Shao, C. Liao, I. Gregg, P. A. Davoudian, N. K. Savalia, K. Delagarza, and A. C. Kwan, "Visualizing drug actions on dendrites: psilocybin and other classic psychedelics," in Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN), Technical Digest Series (Optica Publishing Group, 2023), paper BTu2B.2.

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Abstract

To determine effects of psychedelics on neuronal architecture, we used two-photon microscopy to image dendritic spines in mouse frontal cortex after administering psilocybin (Neuron, 109, 2535, 2021) and compared with other psychoactive drugs.

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