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Optica Publishing Group
  • Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)
  • Technical Digest Series (Optica Publishing Group, 2023),
  • paper OTu3E.4
  • https://doi.org/10.1364/OMP.2023.OTu3E.4

Fluorescent imaging of synaptic glutamate transients in defined neuronal circuits

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Abstract

A splittable genetically encoded intensimetric fluorescent sensor for glutamate is engineered. It can reconstitute across synaptic clefts and report glutamate transients when the nonfluorescent halves are targeted to pre- and post-synaptic neurons in a circuit.

© 2023 The Author(s)

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