Peptides Functionalized Carbon Dots For In Vitro Fluorescent Imaging Of Amyloid Fibrils

Yang Xia; Parasuraman Padmanabhan; Balázs Gulyás; Vadakke Matham Murukeshan

2017 Conference on Lasers and Electro-Optics Pacific Rim
(Optica Publishing Group, 2017),
paper s1509

Peptides Functionalized Carbon Dots For In Vitro Fluorescent Imaging Of Amyloid Fibrils

Yang Xia, Parasuraman Padmanabhan, Balázs Gulyás, and Vadakke Matham Murukeshan

Conference on Lasers and Electro-Optics/Pacific Rim 2017

Singapore Singapore
31 July–4 August 2017
ISBN: 978-1-5090-6290-4

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Poster Session IV (PSIV)

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Y. Xia, P. Padmanabhan, B. Gulyás, and V. M. Murukeshan, "Peptides Functionalized Carbon Dots For In Vitro Fluorescent Imaging Of Amyloid Fibrils," in 2017 Conference on Lasers and Electro-Optics Pacific Rim, (Optica Publishing Group, 2017), paper s1509.

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Abstract

Carbon dots (C-dots) with an average size of 6 nm was synthesized by hydrothermal pyrolysis of sucrose. The C-dots were further conjugated with amyloid beta 42 peptides. The functionalized C-dots were then used to localize the amyloid fibrils. The results show that the C-dots is a potential fluorescent probes for amyloid imaging.

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