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Tether-less Implantable Upconverting Microscale Light Bulbs for Deep Brain Neural Stimulation and Imaging

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We demonstrate the design and fabrication of implantable micro-scale light “bulbs” comprising of parylene-encapsulated upconverting lanthanide-doped nanocrystals (absorbing near-infrared and emitting blue light) for non-invasive targeted optogenetic stimulation of local neuronal ensembles.

© 2015 Optical Society of America

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