Dual-Comb Biosensing for Rapid Detection of SARS-CoV-2

S. Miyamura; S. Miyamura; R. Oe; R. Oe; T. Nakahara; T. Nakahara; S. Okada; T. Kajisa; T. Kajisa; S. Taue; Y. Tokizane; T. Minamikawa; T. Yano; K. Otsuka; K. Otsuka; A. Sakane; A. Sakane; T. Sasaki; T. Sasaki; K. Yasutomo; K. Yasutomo; T. Yasui

doi:10.1364/CLEO_AT.2022.JTh6A.6

Conference on Lasers and Electro-Optics
Technical Digest Series (Optica Publishing Group, 2022),
paper JTh6A.6
•https://doi.org/10.1364/CLEO_AT.2022.JTh6A.6

Dual-Comb Biosensing for Rapid Detection of SARS-CoV-2

S. Miyamura, R. Oe, T. Nakahara, S. Okada, T. Kajisa, S. Taue, Y. Tokizane, T. Minamikawa, T. Yano, K. Otsuka, A. Sakane, T. Sasaki, K. Yasutomo, and T. Yasui

CLEO: Applications and Technology 2022

San Jose, California United States
15–20 May 2022
ISBN: 978-1-957171-05-0

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Joint Postdeadline Presentation Session I (JTh6A)

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S. Miyamura, R. Oe, T. Nakahara, S. Okada, T. Kajisa, S. Taue, Y. Tokizane, T. Minamikawa, T. Yano, K. Otsuka, A. Sakane, T. Sasaki, K. Yasutomo, and T. Yasui, "Dual-Comb Biosensing for Rapid Detection of SARS-CoV-2," in Conference on Lasers and Electro-Optics, Technical Digest Series (Optica Publishing Group, 2022), paper JTh6A.6.

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Abstract

We demonstrated rapid detection of SARS-CoV-2 nucleocapsid protein antigen by dual-comb biosensing with surface modification of its corresponding antibody. A sensitivity close to that of RT-PCR was achieved, thanks to the use of active–dummy temperature compensation.

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