Abstract

Elaboration of the efficient set for hema- toporphyrin derivative photodynamic therapy [HpD-PDT] diagnostic and therapy, require the knowledge about the absorption spectrum of a photosensibilizer. Our work is based on HpD synthesized by A. Graczyk's team,¹ and spectrum is presented in Fig. 1. As it is known the absorption spectrum of HpD depends on the composition and kind of absorbing tissue as well as on the individual features of a patient.^1,3 The efficient use of the HpD for diagnosis and therapy of tumours requires an application of the light sources with a relatively narrow spectral line, enabling a radiation emission within the range of 610-630 nm (therapy) and of 350-420 nm (diagnostics). Red radiation is used for therapy, in spite of a weak absorption for Hp, considering its relatively significant penetration in the tissues.

© 1994 IEEE