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Conferences > CLEO_Europe > 2001 > PS > PS123
  • Laser 2001 - World of Photonics 15th International Conference on Lasers and Electrooptics in Europe
  • Technical Digest Series (Optica Publishing Group, 2001),
  • paper PS123

Aqueous samples for Matrix Assisted Laser Desorption and Ionisation Mass-Spectroscopy

Th. Huber, W. Lüthy, and H.P. Weber

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Abstract

Matrix assisted laser desorption and ionisation is an important technique in the analysis of organic material. In a standard MALDI [1] setup, the Matrix consists of a crystalline material, with an UV or IR laser for desorption. The use of a water-based Matrix makes it possible to measure organic materials directly in their natural environments. The high absorption of water at 2.8 µm makes the Er3+ laser predestined for desorption. The lower photon energy compared to the UV avoids photochemical breakup of sensitive organic macromolecules.

© 2001 EPS

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