Abstract
Intensive research efforts have been drawn on the development of biosensors for early cancer diagnosis. To achieve the goal, surface-enhanced Raman spectroscopy (SERS) is a promising tool in light of its excellent specificity and non-invasive nature [1,2]. However, SERS biosensors currently face two challenges: i) tedious surface functionalization; ii) signal fluctuation. To address these issues, we used Al nanoparticles to naturally immobilize DNA and InGaN quantum wells to stabilize the SERS signals via abundant surface charges [3]. These solutions significantly simplify the detection steps and render the sensitivity to the single-molecule level.
© 2023 IEEE
PDF ArticleMore Like This
Sathi Das, Vrishty Kundu, Arijit Pal, Kanchan Saxena, Vivekanandan Perumal, and Dalip Singh Mehta
126272H European Conference on Biomedical Optics (ECBO) 2023
Lindsay M. Freeman, Lin Pang, and Yeshaiahu Fainman
FM2H.1 CLEO: QELS_Fundamental Science (CLEO:FS) 2017
Thi Anh Nguyet Nguyen, Kun-Yu Lai, and Fan-Ching Chien
OFA2B_03 International Conference on Optics-Photonics Design and Fabrication (ODF) 2022