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Single-cell Fourier-transform light scattering analysis by high- throughput label-free imaging flow cytometry

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Abstract

We report a high-throughput imaging flow cytometer that employs Fourier-transform light-scattering analysis to parametrize high-resolution single-cell morphology, notably subcellular mass-density fractal pattern, as sensitive label-free phenotypes to identify different cell types and states.

© 2020 The Author(s)

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