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  • Translational Biophotonics: Diagnostics and Therapeutics III
  • Technical Digest Series (Optica Publishing Group, 2023),
  • paper 1262734
  • https://doi.org/10.1117/12.2670677

Study of Lipid Involvement in Breast Cancer by using Vibrational Imaging on Tissue Samples from Normal and Obese Patients

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Abstract

Breast cancer has become the most diagnosed cancer globally, replacing lung cancer in 2020, with 2.3 million new cases and an estimated death of 685000 women. It is predicted that by the year of 2040 there would be an increase to around 3 million new cases and 1 million deaths worldwide. This calls for techniques for better and faster diagnosis, and in understanding the different biomarkers and the resulting metabolic alterations aiding the development and progression of the tumour. Obesity is associated with metabolic alterations that have shown to increase the risk of cancer and worsen its prognosis. It is associated with dysfunction of adipose tissue that alter the lipid metabolism resulting in excessive accumulation of adipose tissue at sites other than where they are classically found.

© 2023 SPIE

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