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  • Optical Coherence Imaging Techniques and Imaging in Scattering Media V
  • Technical Digest Series (Optica Publishing Group, 2023),
  • paper 126320O
  • https://doi.org/10.1117/12.2670568

Ultrafast volumetric imaging with a Spatio-Temporal Optical Coherence Tomography (STOC-T) system for monitoring hemodynamics in mouse retinal vessels directly from structural data

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Abstract

We present a novel ultrafast imaging system using Spatio-Temporal Optical Coherence Tomography (STOC-T), capable of acquiring structural images of a mouse retina at a volumetric rate of 112 Hz. A calibrated fundus camera and white-light illumination aid the alignment of the mouse and the adjustment of the focal plane in the mouse retina for the STOC-T image. We extract pulsatile blood flow frequency and other hemodynamic parameters from multiple retinal and choroidal vessels from structural-only OCT images, highlighting the prospects of STOC-T for monitoring retinal hemodynamics in a simple way.

© 2023 SPIE

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