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Spatio-Temporal Optical Coherence Tomography (STOC-T) is a new imaging modality that uses light with controlled spatial and temporal coherence. The retinal images acquired with the STOC-T system maintain high resolution in all three dimensions, over the entire thickness of about 700 μm, without mechanical scanning. We have employed known data processing algorithms and developed new ones to handle and process the acquired data sets to produce highly- corrected 3D data for retinas over large fields of view. The technology and algorithms used here enabled high transverse resolution imaging of the retina and the choroid at various depths, making the differentiation of morphology visible for the first time within the Sattler's, Haller's, and choriocapillaris layers. Visualization of choroidal layers was carried out by using the STOCT angio algorithm. We analyzed the acquired data quantitatively to identify an effective biomarker.
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