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The Effect of a Topical Beta-Adrenergic Receptor Antagonist on the Dynamics of Steady-State Accommodation

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Abstract

Temporal fluctuations in the steady-state human ocular accommodation response are characterised by two principal frequency components: a high frequency component (HFC: 1-2.2Hz) and a low frequency component (LFC:<0.5Hz) (Campbell, Robson and Westheimer, 1959; Kotulak and Schor, 1986; Winn et al, 1989). Recent work has demonstrated that the location of the HFC is significantly correlated with arterial pulse (Winn et al, 1990). These findings have led to the proposal that the HFCs are not governed by an accommodative control system, although they may potentially be utilised in conjunction with the LFCs by a sensory detection system which monitors retinal image contrast during steady-state accommodation. Further, HFCs could provide a useful non-invasive technique for investigating the ocular consequences of arterial pulse (AP).

© 1991 Optical Society of America

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