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Conferences > NTM > 2023 > JTu4B > JTu4B.19

Correlated Structural and Functional Deficits in a Mouse Model of Demyelination

Aniruddha Das, Julie Borovicka, Jacob Icardi, Priyanka Agochiya, Shriya Singh, and Hod Dana

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Abstract

Concurrent two-photon and third-harmonic generation microscopy recordings from the hippocampus of mice fed with cuprizone to induced demyelination showed a correlation between the severity of myelin loss and reduced neuronal firing in the same mice.

© 2023 The Author(s)

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