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Conferences > BODA > 2023 > DTu2A > DTu2A.5

A Platform for Single Cell Optogenetics to Study Synaptic Engrams in Vitro

Clara Zaccaria, Asiye Malkoç, Beatrice Vignoli, Marco Canossa, and Lorenzo Pavesi

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Abstract

Memory relies on the firing of simultaneously activated neurons (engram), whose synapses are strengthened by long-term potentiation mechanisms. Optogenetic tools and a fluorescence probe to map synaptic engrams, were combined with a digital light processor device (DLP), to create in-vitro engrams and study populations of potentiated spines.

© 2023 The Author(s)

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