Abstract

In many ocular diseases the retinal thickness is altered due to edema or atrophy. We have developed a method to measure the retinal thickness and thus provide earlier diagnosis and improve therapy monitoring. The application in humans has provided encouraging results. (1,2) To establish the method further, comparison between in vivo and in vitro thickness measurements in the same eye are desirable. The layers from which light is reflected and detected by the in vivo method can be identified and more information about the presence of tissue distortions arising from the in vitro method during preparation can be acquired. We present the comparison between locally measured thickness values in a cynomolgus monkey and measurements made by light microscopy of the whole mounted retina.

© 1991 Optical Society of America