Multimodal vibrational and multi-photon nonlinear optical microscopy to assess chemotherapy-induced senescence in human cancer cells

Arianna Bresci; Francesco Manetti; Silvia Ghislanzoni; Benedetta Talone; Federico Vernuccio; Alejandro De la Cadena; Chiara Ceconello; Renzo Vanna; Giulio Cerullo; Giulio Cerullo; Italia Bongarzone; Dario Polli; Dario Polli

doi:10.1364/UP.2022.M4A.4

The International Conference on Ultrafast Phenomena (UP) 2022
Technical Digest Series (Optica Publishing Group, 2022),
paper M4A.4
•https://doi.org/10.1364/UP.2022.M4A.4

Multimodal vibrational and multi-photon nonlinear optical microscopy to assess chemotherapy-induced senescence in human cancer cells

Arianna Bresci, Francesco Manetti, Silvia Ghislanzoni, Benedetta Talone, Federico Vernuccio, Alejandro De la Cadena, Chiara Ceconello, Renzo Vanna, Giulio Cerullo, Italia Bongarzone, and Dario Polli

International Conference on Ultrafast Phenomena 2022

Montreal, Quebec Canada
18–22 July 2022
ISBN: 978-1-957171-07-4

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A. Bresci, F. Manetti, S. Ghislanzoni, B. Talone, F. Vernuccio, A. De la Cadena, C. Ceconello, R. Vanna, G. Cerullo, I. Bongarzone, and D. Polli, "Multimodal vibrational and multi-photon nonlinear optical microscopy to assess chemotherapy-induced senescence in human cancer cells," in The International Conference on Ultrafast Phenomena (UP) 2022, F. Légaré, T. Tahara, J. Biegert, T. Brixner, and N. Dudovich, eds., Technical Digest Series (Optica Publishing Group, 2022), paper M4A.4.

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Abstract

We introduce label-free multimodal nonlinear optical microscopy, based on different coherent Raman and multi-photon ultrafast light-matter interactions, as a noninvasive, quantitative and chemically selective tool to assess chemotherapy-induced senescence in human cancer cells.

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