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Scattered Light Tomography: Instrumentation and Ocular Fundus Data with A Vertical Cavity Surface Emitting Laser

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Abstract

We present a new technique for multiply scattered light tomography, as well as first results, designed to probe the relative thickness and depth of ocular structures. Previous studies have shown that the relative thickness and depth of retinal and subretinal structures provides crucial information in the pathophysiology, progression, and treatment of many eye diseases. Recent noninvasive imaging techniques using scanning laser ophthalmoscopy and near infrared light have demonstrated: a) differences in thickness of the nerve fiber layer in glaucoma as opposed to normal eyes1,b) development of drusen in eyes of adults prior to clinical visualization2, c) widespread and otherwise undetected drusen in eyes with neovascularization3, and d) thickening as an early sign of neovascular membranes in age-related macular degeneration3,4.

© 1997 Optical Society of America

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