Label-free Longitudinal Imaging of Cortical Myelin through Intact Mouse Skull Using Computational Conjugate Adaptive Optics

Jin Hee Hong; Jin Hee Hong; Yongwoo Kwon; Yongwoo Kwon; Seokchan Yoon; Seokchan Yoon; Sungsam Kang; Sungsam Kang; Hojun Lee; Wonshik Choi; Wonshik Choi

doi:10.1364/3D.2022.JTh2A.16

Imaging and Applied Optics Congress 2022 (3D, AOA, COSI, ISA, pcAOP)
Technical Digest Series (Optica Publishing Group, 2022),
paper JTh2A.16
•https://doi.org/10.1364/3D.2022.JTh2A.16

Label-free Longitudinal Imaging of Cortical Myelin through Intact Mouse Skull Using Computational Conjugate Adaptive Optics

Jin Hee Hong, Yongwoo Kwon, Seokchan Yoon, Sungsam Kang, Hojun Lee, and Wonshik Choi

Propagation Through and Characterization of Atmospheric and Oceanic Phenomena 2022

Vancouver, British Columbia Canada
11–15 July 2022
ISBN: 978-1-957171-09-8

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Joint Poster Session III (On-Site) (JTh2A)

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J. H. Hong, Y. Kwon, S. Yoon, S. Kang, H. Lee, and W. Choi, "Label-free Longitudinal Imaging of Cortical Myelin through Intact Mouse Skull Using Computational Conjugate Adaptive Optics," in Imaging and Applied Optics Congress 2022 (3D, AOA, COSI, ISA, pcAOP), Technical Digest Series (Optica Publishing Group, 2022), paper JTh2A.16.

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Abstract

We developed a reflection matrix microscopy using a 1.3-μm wavelength and computational adaptive optics. This could realize a longitudinal study of myelin in the mouse brain within 8 weeks up to cortical layer 4 through the intact skull.

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