Polarization and Orbital Angular Momentum of Light in Biomedical Applications: feature issue introduction

Igor Meglinski, Tatiana Novikova, and Kishan Dholakia

Biomed. Opt. Express 12(10), 6255-6258 (2021)  View: HTML | PDF

Correntropy-induced metric with Laplacian kernel for robust fluorescence molecular tomography

Yating Yuan, Hongbo Guo, Huangjian Yi, Jingjing Yu, Xuelei He, and Xiaowei He

Biomed. Opt. Express 12(10), 5991-6012 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Influence of the anatomical features of different brain regions on the spatial localization of fiber photometry signals

Cinzia Montinaro, Marco Pisanello, Marco Bianco, Barbara Spagnolo, Filippo Pisano, Antonio Balena, Francesco De Nuccio, Dario Domenico Lofrumento, Tiziano Verri, Massimo De Vittorio, and Ferruccio Pisanello

Biomed. Opt. Express 12(10), 6081-6094 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Multi-window sparse spectral sampling stimulated Raman scattering microscopy

Isaac J. Pence, Benjamin A. Kuzma, Maximilian Brinkmann, Tim Hellwig, and Conor L. Evans

Biomed. Opt. Express 12(10), 6095-6114 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Label-free automated neutropenia detection and grading using deep-ultraviolet microscopy

Ashkan Ojaghi, Paloma Casteleiro Costa, Christina Caruso, Wilbur A. Lam, and Francisco E. Robles

Biomed. Opt. Express 12(10), 6115-6128 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

In vivo harmonic generation microscopy for monitoring the height of basal keratinocytes in solar lentigines after laser depigmentation treatment

Pei-Jhe Wu, Sheng-Tse Chen, Yi-Hua Liao, and Chi-Kuang Sun

Biomed. Opt. Express 12(10), 6129-6142 (2021)  View: HTML | PDF

Analysis of intracellular protein dynamics in living zebrafish embryos using light-sheet fluorescence single-molecule microscopy

Matteo Bernardello, Radoslaw J. Gora, Patrick Van Hage, Gustavo Castro-Olvera, Emilio J. Gualda, Marcel J. M. Schaaf, and Pablo Loza-Alvarez

Biomed. Opt. Express 12(10), 6205-6227 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Multi-color stimulated Raman scattering with a frame-to-frame wavelength-tunable fiber-based light source

Thomas Würthwein, Kristin Wallmeier, Maximilian Brinkmann, Tim Hellwig, Niklas M. Lüpken, Nick S. Lemberger, and Carsten Fallnich

Biomed. Opt. Express 12(10), 6228-6236 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Light-sheet fluorescence microscopy for the in vivo study of microtubule dynamics in the zebrafish embryo

Matteo Bernardello, Maria Marsal, Emilio J. Gualda, and Pablo Loza-Alvarez

Biomed. Opt. Express 12(10), 6237-6254 (2021)  View: HTML | PDF  [Suppl. Mat. (8)]

Heterodyne Brillouin microscopy for biomechanical imaging

Michael A. Taylor, Amanda W. Kijas, Zhao Wang, Jan Lauko, and Alan E. Rowan

Biomed. Opt. Express 12(10), 6259-6268 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Femtosecond diode-based time lens laser for multiphoton microscopy

Y. Lange Simmons, Kenneth J. Underwood, Omkar D. Supekar, Brendan M. Heffernan, Tarah A. Welton, Emily A. Gibson, and Juliet T. Gopinath

Biomed. Opt. Express 12(10), 6269-6276 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Improved microscopy with ultraviolet surface excitation (MUSE) using high-index immersion illumination

Vincent D. Ching-Roa, Chi Z. Huang, and Michael G. Giacomelli

Biomed. Opt. Express 12(10), 6461-6473 (2021)  View: HTML | PDF

Deep-skin multiphoton microscopy of lymphatic vessels excited at the 1700-nm window in vivo

Ke Wang, Yi Pan, Shen Tong, Huiping Liang, and Ping Qiu

Biomed. Opt. Express 12(10), 6474-6484 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Self-supervised pretraining for transferable quantitative phase image cell segmentation

Tomas Vicar, Jiri Chmelik, Roman Jakubicek, Larisa Chmelikova, Jaromir Gumulec, Jan Balvan, Ivo Provaznik, and Radim Kolar

Biomed. Opt. Express 12(10), 6514-6528 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Optical neural stimulation using the thermoplasmonic effect of gold nano-hexagon

Hassan Tajarenejad, Mohammad Ali Ansari, Soheila Akbari, Hanieh Yazdanfar, and Seyedeh Mehri Hamidi

Biomed. Opt. Express 12(10), 6013-6023 (2021)  View: HTML | PDF

Spectrally-selective mid-IR laser-induced inactivation of pathogenic bacteria

Victor Kompanets, Svetlana Shelygina, Eteri Tolordava, Sergey Kudryashov, Irina Saraeva, Aleksey Rupasov, Olga Baitsaeva, Roman Khmelnitskii, Andrey Ionin, Yulia Yushina, Sergey Chekalin, and Michael Kovalev

Biomed. Opt. Express 12(10), 6317-6325 (2021)  View: HTML | PDF

Nicotinamide effects on the metabolism of human fibroblasts and keratinocytes assessed by quantitative, label-free fluorescence imaging

Zhiyi Liu, Chung-Yi Chiang, John Nip, Lin Feng, Yang Zhang, Sheila Rocha, and Irene Georgakoudi

Biomed. Opt. Express 12(10), 6375-6390 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Real-time monitoring of the sucrose hydrolysis process based on two-photon coincidence measurements

Zheng Peng, Zhiyuan Zhou, Tongju Li, Meili Jiang, Chenhao Li, Tang Qing, Liu Yang, and Xiaochun Zhang

Biomed. Opt. Express 12(10), 6590-6600 (2021)  View: HTML | PDF

Reflection-type photoplethysmography pulse sensor based on an integrated optoelectronic chip with a ring structure

Jiabin Yan, Ziqi Ye, Fan Shi, Yeling Dai, Lingyun Yang, Jie Wu, and Yongjin Wang

Biomed. Opt. Express 12(10), 6277-6283 (2021)  View: HTML | PDF

Signal properties of split-spectrum amplitude decorrelation angiography for quantitative optical coherence tomography-based velocimetry

Yu Nakamichi, Kai-shih Chiu, and Chia-Wei Sun

Biomed. Opt. Express 12(10), 5955-5968 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Retinal adaptive optics imaging with a pyramid wavefront sensor

Elisabeth Brunner, Julia Shatokhina, Muhammad Faizan Shirazi, Wolfgang Drexler, Rainer Leitgeb, Andreas Pollreisz, Christoph K. Hitzenberger, Ronny Ramlau, and Michael Pircher

Biomed. Opt. Express 12(10), 5969-5990 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast

Michael Münter, Mario Pieper, Tabea Kohlfaerber, Ernst Bodenstorfer, Martin Ahrens, Christian Winter, Robert Huber, Peter König, Gereon Hüttmann, and Hinnerk Schulz-Hildebrandt

Biomed. Opt. Express 12(10), 6024-6039 (2021)  View: HTML | PDF  [Suppl. Mat. (4)]

Connectivity-based deep learning approach for segmentation of the epithelium in in vivo human esophageal OCT images

Ziyun Yang, Somayyeh Soltanian-Zadeh, Kengyeh K. Chu, Haoran Zhang, Lama Moussa, Ariel E. Watts, Nicholas J. Shaheen, Adam Wax, and Sina Farsiu

Biomed. Opt. Express 12(10), 6326-6340 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Estimation of scleral mechanical properties from air-puff optical coherence tomography

David Bronte-Ciriza, Judith S. Birkenfeld, Andrés de la Hoz, Andrea Curatolo, James A. Germann, Lupe Villegas, Alejandra Varea, Eduardo Martínez-Enríquez, and Susana Marcos

Biomed. Opt. Express 12(10), 6341-6359 (2021)  View: HTML | PDF

Investigation of the scattering and attenuation properties of cataracts formed in mouse eyes with 1060-nm and 1310-nm swept-source optical coherence tomography

Pablo Eugui, Conrad W. Merkle, Johanna Gesperger, Antonia Lichtenegger, and Bernhard Baumann

Biomed. Opt. Express 12(10), 6391-6406 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Statistical analysis of corneal OCT speckle: a non-parametric approach

Marcela Niemczyk and D. Robert Iskander

Biomed. Opt. Express 12(10), 6407-6421 (2021)  View: HTML | PDF

Quantitative evaluation of the dynamic activity of HeLa cells in different viability states using dynamic full-field optical coherence microscopy

Soongho Park, Thien Nguyen, Emilie Benoit, Dan L. Sackett, Marcial Garmendia-Cedillos, Randall Pursley, Claude Boccara, and Amir Gandjbakhche

Biomed. Opt. Express 12(10), 6431-6441 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Effect of optical coherence tomography and angiography sampling rate towards diabetic retinopathy severity classification

Timothy T. Yu, Da Ma, Julian Lo, Myeong Jin Ju, Mirza Faisal Beg, and Marinko V. Sarunic

Biomed. Opt. Express 12(10), 6660-6673 (2021)  View: HTML | PDF

Monitoring subcutaneous tumors using Mueller polarimetry: study on two types of tumors

Briséis Varin, Jean Rehbinder, Jean Dellinger, Christian Heinrich, Marc Torzynski, Caroline Spenlé, Dominique Bagnard, and Jihad Zallat

Biomed. Opt. Express 12(10), 6055-6065 (2021)  View: HTML | PDF

Bayesian deep learning for reliable oral cancer image classification

Bofan Song, Sumsum Sunny, Shaobai Li, Keerthi Gurushanth, Pramila Mendonca, Nirza Mukhia, Sanjana Patrick, Shubha Gurudath, Subhashini Raghavan, Imchen Tsusennaro, Shirley T. Leivon, Trupti Kolur, Vivek Shetty, Vidya R. Bushan, Rohan Ramesh, Tyler Peterson, Vijay Pillai, Petra Wilder-Smith, Alben Sigamani, Amritha Suresh, moni Abraham Kuriakose, Praveen Birur, and Rongguang Liang

Biomed. Opt. Express 12(10), 6422-6430 (2021)  View: HTML | PDF

Nomogram model combining macro and micro tumor-associated collagen signatures obtained from multiphoton images to predict the histologic grade in breast cancer

Gangqin Xi, Jiajia He, Deyong Kang, Shuoyu Xu, Wenhui Guo, Fangmeng Fu, Yulan Liu, Liqin Zheng, Lida Qiu, Lianhuang Li, Chuan Wang, and Jianxin Chen

Biomed. Opt. Express 12(10), 6558-6570 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Polarimetric visualization of healthy brain fiber tracts under adverse conditions: ex vivo studies

Omar Rodríguez-Núñez, Philippe Schucht, Ekkehard Hewer, Tatiana Novikova, and Angelo Pierangelo

Biomed. Opt. Express 12(10), 6674-6685 (2021)  View: HTML | PDF

Optoelectronic manipulation of bio-droplets containing cells or macromolecules by active ferroelectric platforms

Andrés Puerto, José L. Bella, Carmen López-Fernández, Angel García-Cabañes, and Mercedes Carrascosa

Biomed. Opt. Express 12(10), 6601-6613 (2021)  View: HTML | PDF  [Suppl. Mat. (4)]

Denoising of pre-beamformed photoacoustic data using generative adversarial networks

Amir Refaee, Corey J. Kelly, Hamid Moradi, and Septimiu E. Salcudean

Biomed. Opt. Express 12(10), 6184-6204 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Artifact removal in photoacoustic tomography with an unsupervised method

Mengyang Lu, Xin Liu, Chengcheng Liu, Boyi Li, Wenting Gu, Jiehui Jiang, and Dean Ta

Biomed. Opt. Express 12(10), 6284-6299 (2021)  View: HTML | PDF

Quantitative and anatomical imaging of dermal angiopathy by noninvasive photoacoustic microscopic biopsy

Haigang Ma, Zhongwen Cheng, Zhiyang Wang, Haixia Qiu, Tianding Shen, Da Xing, Ying Gu, and Sihua Yang

Biomed. Opt. Express 12(10), 6300-6316 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Dual-model wearable photoacoustic microscopy and electroencephalograph: study of neurovascular coupling in anesthetized and freely moving rats

Qian Chen, Tian Jin, Weizhi Qi, and Lei Xi

Biomed. Opt. Express 12(10), 6614-6628 (2021)  View: HTML | PDF  [Suppl. Mat. (8)]

Most favorable stimulation duration in the sensorimotor cortex for fNIRS-based BCI

M. N. Afzal Khan and Keum-Shik Hong

Biomed. Opt. Express 12(10), 5939-5954 (2021)  View: HTML | PDF

Articular cartilage optical properties in the near-infrared (NIR) spectral range vary with depth and tissue integrity

Bilour Khan, Iman Kafian-Attari, Ervin Nippolainen, Rubina Shaikh, Dmitry Semenov, Markku Hauta-Kasari, Juha Töyräs, and Isaac O. Afara

Biomed. Opt. Express 12(10), 6066-6080 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

In vivo two-dimensional quantitative imaging of skin and cutaneous microcirculation with perturbative spatial frequency domain imaging (p-SFDI)

Weihao Lin, Yang Zheng, Zhenfang Li, Xin Jin, Zili Cao, Bixin Zeng, and M. Xu

Biomed. Opt. Express 12(10), 6143-6156 (2021)  View: HTML | PDF

Compressed sensing time-resolved spectrometer for quantification of light absorbers in turbid media

Seva Ioussoufovitch, David Jonathan Fulop Cohen, Daniel Milej, and Mamadou Diop

Biomed. Opt. Express 12(10), 6442-6460 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Measuring pupil size and light response through closed eyelids

Yousef Farraj, Amnon Buxboim, Jose E. Cohen, Yoav Kan-Tor, Shira Glasner Hagege, Dor Weiss, Vladimir Goldman, and Tsevi Beatus

Biomed. Opt. Express 12(10), 6485-6495 (2021)  View: HTML | PDF

Time-domain NIRS system based on supercontinuum light source and multi-wavelength detection: validation for tissue oxygenation studies

Aleh Sudakou, Frédéric Lange, Helene Isler, Pranav Lanka, Stanislaw Wojtkiewicz, Piotr Sawosz, Daniel Ostojic, Martin Wolf, Antonio Pifferi, Ilias Tachtsidis, Adam Liebert, and Anna Gerega

Biomed. Opt. Express 12(10), 6629-6650 (2021)  View: HTML | PDF

SLM-based interferometer for assessing the polychromatic neural transfer function of the eye

Nikolai Suchkov, Tobin Kurian, Christina Schwarz, Alexander Leube, and Siegfried Wahl

Biomed. Opt. Express 12(10), 6040-6054 (2021)  View: HTML | PDF

Imaging the dynamics of individual processes of microglia in the living retina in vivo

Aby Joseph, Derek Power, and Jesse Schallek

Biomed. Opt. Express 12(10), 6157-6183 (2021)  View: HTML | PDF  [Suppl. Mat. (9)]

Optical and visual quality of real intraocular lenses physically projected on the patient’s eye

Clara Benedi-Garcia, Maria Vinas, Carmen M Lago, Sara Aissati, Alberto de Castro, Carlos Dorronsoro, and Susana Marcos

Biomed. Opt. Express 12(10), 6360-6374 (2021)  View: HTML | PDF

Hybrid FPGA-CPU pupil tracker

Bartlomiej Kowalski, Xiaojing Huang, Samuel Steven, and Alfredo Dubra

Biomed. Opt. Express 12(10), 6496-6513 (2021)  View: HTML | PDF

GDCSeg-Net: general optic disc and cup segmentation network for multi-device fundus images

Qianlong Zhu, Xinjian Chen, Qingquan Meng, Jiahuan Song, Gaohui Luo, Meng Wang, Fei Shi, Zhongyue Chen, Dehui Xiang, Lingjiao Pan, Zuoyong Li, and Weifang Zhu

Biomed. Opt. Express 12(10), 6529-6544 (2021)  View: HTML | PDF

Understanding the relationship between visual-angle and eye-angle for reliable determination of the field-of-view in ultra-wide field fundus photography

Xincheng Yao, Devrim Toslak, Taeyoon Son, and Jiechao Ma

Biomed. Opt. Express 12(10), 6651-6659 (2021)  View: HTML | PDF