Mueller matrix polarimetry and polar decomposition of articular cartilage imaged in reflectance

Ruby N. Huynh, George Nehmetallah, and Christopher B. Raub

Biomed. Opt. Express 12(8), 5160-5178 (2021)  View: HTML | PDF

Label-free microscopy of mitotic chromosomes using the polarization orthogonality breaking technique

Rajesh Desapogu, Gilles Le Marchand, Rebecca Smith, Paulami Ray, Émilie Gillier, Stéphanie Dutertre, Mehdi Alouini, Marc Tramier, Sébastien Huet, and Julien Fade

Biomed. Opt. Express 12(8), 5290-5304 (2021)  View: HTML | PDF

Stokes polarization imaging applied for monitoring dynamic tissue optical clearing

Jiawei Song, Nan Zeng, Wei Guo, Jun Guo, and Hui Ma

Biomed. Opt. Express 12(8), 4821-4836 (2021)  View: HTML | PDF

Polarimetric data-based model for tissue recognition

Carla Rodríguez, Albert Van Eeckhout, Laia Ferrer, Enrique Garcia-Caurel, Emilio González-Arnay, Juan Campos, and Angel Lizana

Biomed. Opt. Express 12(8), 4852-4872 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Three-compartment-breast (3CB) prior-guided diffuse optical tomography based on dual-energy digital breast tomosynthesis (DBT)

Sungho Yun, Yejin Kim, Hyeongseok Kim, Seoyoung Lee, Uijin Jeong, Hoyeon Lee, Young-wook Choi, and Seungryong Cho

Biomed. Opt. Express 12(8), 4837-4851 (2021)  View: HTML | PDF

Ultrasound segmentation-guided edge artifact reduction in diffuse optical tomography using connected component analysis

Shuying Li, Menghao Zhang, and Quing Zhu

Biomed. Opt. Express 12(8), 5320-5336 (2021)  View: HTML | PDF

Fiber optic probe with functional polymer composites for hyperthermia

Alexa Hernández-Arenas, Reinher Pimentel-Domínguez, J. Rodrigo Vélez-Cordero, and Juan Hernández-Cordero

Biomed. Opt. Express 12(8), 4730-4744 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Ultrafast laser surgery probe with a calcium fluoride miniaturized objective for bone ablation

Kaushik Subramanian, Liam Andrus, Michal Pawlowski, Ye Wang, Tomasz Tkaczyk, and Adela Ben-Yakar

Biomed. Opt. Express 12(8), 4779-4794 (2021)  View: HTML | PDF

Brightfield, fluorescence, and phase-contrast whole slide imaging via dual-LED autofocusing

Chengfei Guo, Zichao Bian, Soliman Alhudaithy, Shaowei Jiang, Yuji Tomizawa, Pengming Song, Tianbo Wang, and Xiaopeng Shao

Biomed. Opt. Express 12(8), 4651-4660 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Single-laser-based simultaneous four-wavelength excitation source for femtosecond two-photon fluorescence microscopy

Yang-Ting Hsiao, Yu-Fan Huang, Bhaskar Jyoti Borah, Shih-Kuo Chen, and Chi-Kuang Sun

Biomed. Opt. Express 12(8), 4661-4679 (2021)  View: HTML | PDF

Computational framework for generating large panoramic super-resolution images from localization microscopy

Yue Du, Chenze Wang, Chen Zhang, Lingyun Guo, Yanzhu Chen, Meng Yan, Qianghui Feng, Mingtao Shang, Weibing Kuang, Zhengxia Wang, and Zhen-Li Huang

Biomed. Opt. Express 12(8), 4759-4778 (2021)  View: HTML | PDF

Real-time 3D single-molecule localization microscopy analysis using lookup tables

Fabian Hauser and Jaroslaw Jacak

Biomed. Opt. Express 12(8), 4955-4968 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Deep learning-based autofocus method enhances image quality in light-sheet fluorescence microscopy

Chen Li, Adele Moatti, Xuying Zhang, H. Troy Ghashghaei, and Alon Greenbaum

Biomed. Opt. Express 12(8), 5214-5226 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Parametric comparison between sparsity-based and deep learning-based image reconstruction of super-resolution fluorescence microscopy

Junjie Chen and Yun Chen

Biomed. Opt. Express 12(8), 5246-5260 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

PhaseRMiC: phase real-time microscope camera for live cell imaging

Chao Chen, Yu-Nan Lu, Huachuan Huang, Keding Yan, Zhilong Jiang, Xiaoliang He, Yan Kong, Cheng Liu, Fei Liu, Liang Xue, and Shouyu Wang

Biomed. Opt. Express 12(8), 5261-5271 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Quantification of scar collagen texture and prediction of scar development via second harmonic generation images and a generative adversarial network

Qing Wang, Weiping Liu, Xinghong Chen, Xiumei Wang, Guannan Chen, and Xiaoqin Zhu

Biomed. Opt. Express 12(8), 5305-5319 (2021)  View: HTML | PDF

A compact photonic resonator absorption microscope for point of care digital resolution nucleic acid molecular diagnostics

Shreya Ghosh, Nantao Li, Yanyu Xiong, Young-Gu Ju, Michael P. Rathslag, Ege G. Onal, Erika Falkiewicz, Manish Kohli, and Brian T. Cunningham

Biomed. Opt. Express 12(8), 4637-4650 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

High-fidelity and rapid cellular-level Mueller matrix imaging for tissue identification with unstained sections

Jiazhi Wang, Yanqiu Li, Chenle Cao, Guodong Zhou, and Li Li

Biomed. Opt. Express 12(8), 4745-4758 (2021)  View: HTML | PDF

Cellular-resolution monitoring of ischemic stroke pathologies in the rat cortex

Sergiy Chornyy, Aniruddha Das, Julie A. Borovicka, Davina Patel, Hugh H. Chan, John K. Hermann, Thomas C. Jaramillo, Andre G. Machado, Kenneth B. Baker, and Hod Dana

Biomed. Opt. Express 12(8), 4901-4919 (2021)  View: HTML | PDF  [Suppl. Mat. (5)]

Specific detection of glucose by an optical weak measurement sensor

Yang Xu, Lixuan Shi, Tian Guan, Cuixia Guo, Suyi Zhong, Chongqi Zhou, Hailong Zhang, Zhangyan Li, Xinhui Xing, Yanhong Ji, Wenyue Xie, Le Liu, and Yonghong He

Biomed. Opt. Express 12(8), 5128-5138 (2021)  View: HTML | PDF

Noninvasive OCT angiography-based blood attenuation measurements correlate with blood glucose level in the mouse retina

Kaiyuan Liu, Tiepei Zhu, Lin Yao, Ziyi Zhang, Huakun Li, Juan Ye, and Peng Li

Biomed. Opt. Express 12(8), 4680-4688 (2021)  View: HTML | PDF

Weakly supervised anomaly segmentation in retinal OCT images using an adversarial learning approach

Jing Wang, Wanyue Li, Yiwei Chen, Wangyi Fang, Wen Kong, Yi He, and Guohua Shi

Biomed. Opt. Express 12(8), 4713-4729 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

An end-to-end network for segmenting the vasculature of three retinal capillary plexuses from OCT angiographic volumes

Yukun Guo, Tristan T. Hormel, Shaohua Pi, Xiang Wei, Min Gao, John C. Morrison, and Yali Jia

Biomed. Opt. Express 12(8), 4889-4900 (2021)  View: HTML | PDF

Closed-loop wavefront sensing and correction in the mouse brain with computed optical coherence microscopy

Siyang Liu, Fei Xia, Xusan Yang, Meiqi Wu, Laurie A. Bizimana, Chris Xu, and Steven G. Adie

Biomed. Opt. Express 12(8), 4934-4954 (2021)  View: HTML | PDF

Framework for quantitative three-dimensional choroidal vasculature analysis using optical coherence tomography

Ashish Saxena, Xinwen Yao, Damon Wong, Jacqueline Chua, Marcus Ang, Quan V. Hoang, Rupesh Agrawal, Michael Girard, Gemmy Cheung, Leopold Schmetterer, and Bingyao Tan

Biomed. Opt. Express 12(8), 4982-4996 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Layer-based, depth-resolved computation of attenuation coefficients and backscattering fractions in tissue using optical coherence tomography

Taylor M. Cannon, Brett E. Bouma, and Néstor Uribe-Patarroyo

Biomed. Opt. Express 12(8), 5037-5056 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Investigating the depolarization property of skin tissue by degree of polarization uniformity contrast using polarization-sensitive optical coherence tomography

Xin Zhou, Sina Maloufi, Daniel C. Louie, Ning Zhang, Qihao Liu, Tim K. Lee, and Shuo Tang

Biomed. Opt. Express 12(8), 5073-5088 (2021)  View: HTML | PDF

In vivo measurement of the attenuation coefficient of the sclera and ciliary muscle

Gabrielle Monterano Mesquita, Disha Patel, Yu-Cherng Chang, Florence Cabot, Marco Ruggeri, Sonia H. Yoo, Arthur Ho, Jean-Marie A. Parel, and Fabrice Manns

Biomed. Opt. Express 12(8), 5089-5106 (2021)  View: HTML | PDF

Rapid pseudo-H&E imaging using a fluorescence-inbuilt optical coherence microscopic imaging system

Sey-En Lin, Dong-Yo Jheng, Kuang-Yu Hsu, Yun-Ru Liu, Wei-Hsiang Huang, Hsiang-Chieh Lee, and Chien-Chung Tsai

Biomed. Opt. Express 12(8), 5139-5158 (2021)  View: HTML | PDF

In vivo functional imaging of the human middle ear with a hand-held optical coherence tomography device

Christopher G. Lui, Wihan Kim, James B. Dewey, Frank D. Macías-Escrivá, Kumara Ratnayake, John S. Oghalai, and Brian E. Applegate

Biomed. Opt. Express 12(8), 5196-5213 (2021)  View: HTML | PDF

Exoscope-based videocapillaroscopy system for in vivo skin microcirculation imaging of various body areas

Alexander S. Machikhin, Mikhail V. Volkov, Demid D. Khokhlov, Ekaterina D. Lovchikova, Andrey V. Potemkin, Inna V. Danilycheva, Irina V. Dorofeeva, and Andrey E. Shulzhenko

Biomed. Opt. Express 12(8), 4627-4636 (2021)  View: HTML | PDF

Deep learning classification of cervical dysplasia using depth-resolved angular light scattering profiles

Haoran Zhang, Wesley Y. Kendall, Evan T. Jelly, and Adam Wax

Biomed. Opt. Express 12(8), 4997-5007 (2021)  View: HTML | PDF

Clinical assessment of W-band spectroscopy for non-invasive detection and monitoring of sustained hyperglycemia

Aldo Moreno-Oyervides, M. Carmen Aguilera-Morillo, María José de la Cruz Fernández, Edurne Lecumberri Pascual, Lucía Llanos Jiménez, Viktor Krozer, and Pablo Acedo

Biomed. Opt. Express 12(8), 5008-5022 (2021)  View: HTML | PDF

Handheld spatial frequency domain imager for noninvasive Sjögren's syndrome labial salivary gland biopsy

Bixin Zeng, Mingrou Guo, Kangyuan Yu, Li Sun, Weihao Lin, Da Pan, Xiaowei Chen, and Min Xu

Biomed. Opt. Express 12(8), 5057-5072 (2021)  View: HTML | PDF

Hyperspectral imaging and robust statistics in non-melanoma skin cancer analysis

Lloyd A. Courtenay, Diego González-Aguilera, Susana Lagüela, Susana del Pozo, Camilo Ruiz-Mendez, Inés Barbero-García, Concepción Román-Curto, Javier Cañueto, Carlos Santos-Durán, María Esther Cardeñoso-Álvarez, Mónica Roncero-Riesco, David Hernandez-Lopez, Diego Guerrero-Sevilla, and Pablo Rodríguez-Gonzalvez

Biomed. Opt. Express 12(8), 5107-5127 (2021)  View: HTML | PDF

Optical dosimeter for selective retinal therapy based on multi-port fiber-optic interferometry

Uihan Kim, Minsung Kwon, Gyeongyeon Jung, Youngnam Kim, Yunam Lee, Seonghun Im, Barry Cense, Hyungsuk Lee, Won-Suk Ohm, and Chulmin Joo

Biomed. Opt. Express 12(8), 4920-4933 (2021)  View: HTML | PDF

Automated microscope-independent fluorescence-guided micropipette

Christopher Miranda, Madeleine R. Howell, Joel F. Lusk, Ethan Marschall, Jarrett Eshima, Trent Anderson, and Barbara S. Smith

Biomed. Opt. Express 12(8), 4689-4699 (2021)  View: HTML | PDF

High-performance surface-enhanced Raman spectroscopy chip integrated with a micro-optical system for the rapid detection of creatinine in serum

Feng Yang, Ping Wen, Gang Li, Zhisen Zhang, Chuang Ge, and Li Chen

Biomed. Opt. Express 12(8), 4795-4806 (2021)  View: HTML | PDF  [Suppl. Mat. (1)]

Characterizing the aggressiveness of prostate cancer using an all-optical needle photoacoustic sensing probe: feasibility study

Linyu Ni, Javed Siddiqui, Aaron M. Udager, Janggun Jo, John T. Wei, Matthew S. Davenport, Paul L. Carson, J. Brian Fowlkes, Xueding Wang, and Guan Xu

Biomed. Opt. Express 12(8), 4873-4888 (2021)  View: HTML | PDF

Hybrid reflection retrieval method for terahertz dielectric imaging of human bone

Suzanna Freer, Cong Sui, Stephen M. Hanham, Liam M. Grover, and Miguel Navarro-Cía

Biomed. Opt. Express 12(8), 4807-4820 (2021)  View: HTML | PDF

Terahertz dielectric spectroscopy and solid immersion microscopy of ex vivo glioma model 101.8: brain tissue heterogeneity

A. S. Kucheryavenko, N. V. Chernomyrdin, A. A. Gavdush, A. I. Alekseeva, P. V. Nikitin, I. N. Dolganova, P. A. Karalkin, A. S. Khalansky, I. E. Spektor, M. Skorobogatiy, V. V. Tuchin, and K. I. Zaytsev

Biomed. Opt. Express 12(8), 5272-5289 (2021)  View: HTML | PDF

Estimation of core body temperature by near-infrared imaging of vein diameter change in the dorsal hand

Mohiuddin Khan Shourav, Syifa Salsabila, Joo-Young Lee, and Jung Kyung Kim

Biomed. Opt. Express 12(8), 4700-4712 (2021)  View: HTML | PDF

Monitoring adaptation of skin tissue oxygenation during cycling ergometer exercise by frequency-domain diffuse optical spectroscopy

Sheng-Hao Tseng, Bo-Jian Liang, Wen Wang, Bo-Xiang Tsai, and Po-Sheng Hu

Biomed. Opt. Express 12(8), 5023-5036 (2021)  View: HTML | PDF

Analysis and improvement of non-contact SpO2 extraction using an RGB webcam

Bing Wei, Xiaopei Wu, Chao Zhang, and Zhao Lv

Biomed. Opt. Express 12(8), 5227-5245 (2021)  View: HTML | PDF  [Suppl. Mat. (2)]

Subjective measurement of the Stiles-Crawford effect with different field sizes

Vinay Kumar Nilagiri, Marwan Suheimat, Andrew J. Lambert, Andrew Turpin, Brian Vohnsen, and David A. Atchison

Biomed. Opt. Express 12(8), 4969-4981 (2021)  View: HTML | PDF

Vision-correcting holographic display: evaluation of aberration correcting hologram

Dongyeon Kim, Seung-Woo Nam, Kiseung Bang, Byounghyo Lee, Seungjae Lee, Youngmo Jeong, Jong-Mo Seo, and Byoungho Lee

Biomed. Opt. Express 12(8), 5179-5195 (2021)  View: HTML | PDF

A compact photonic resonator absorption microscope for point of care digital resolution nucleic acid molecular diagnostics: publisher’s note

Shreya Ghosh, Nantao Li, Yanyu Xiong, Young-Gu Ju, Michael P. Rathslag, Ege G. Onal, Erika Falkiewicz, Manish Kohli, and Brian T. Cunningham

Biomed. Opt. Express 12(8), 5159-5159 (2021)  View: HTML | PDF

Weakly supervised anomaly segmentation in retinal OCT images using an adversarial learning approach: publisher’s note

Jing Wang, Wanyue Li, Yiwei Chen, Wangyi Fang, Wen Kong, Yi He, and Guohua Shi

Biomed. Opt. Express 12(8), 5337-5337 (2021)  View: HTML | PDF