Abstract

A non-invasive analysis method for bottled Tanreqing injection was developed based on near infrared (NIR) spectroscopy. The NIR trans-mission spectra were collected using a home-made accessory. The quality indicators of Tanreqing injection, which include baicalin, ursodesoxycholic acid (UDCA), chenodeoxycholic acid (CDCA), chlorogenic acid (CA), forsythin, total amino acids (TAA) and soluble solid content (SSC), were determined with standard methods. Several outlier samples were eliminated using the Dixon test, leverage and studentised residual test and analogous samples were amalgamated. Partial least squares regression (PLSR) was used for establishing the calibration models with the pre-treated spectra and the reference values. The root mean square errors of prediction (RMSEP) values of external validation samples were 0.098 g L⁻¹, 0.059 g L⁻¹, 0.140 g L⁻¹, 0.038g L⁻¹, 0.007 g L⁻¹, 0.053 g L⁻¹ and 0.538 gL⁻¹ for baicalin, CA, UDCA, CDCA, forsythin, TAA and SSC, respectively, which indicated that the established models possessed satisfactory predictive abilities. The presented method can reduce the workload of product inspection to a large extent. This will allow the sampling proportion to be increased and enable improved quality control during Tanreqing injection production.

© 2012 IM Publications LLP

Hemodynamics of the sternocleidomastoid measured with frequency domain near-infrared spectroscopy towards non-invasive monitoring during mechanical ventilation

Raeef Istfan, Carlos A. Gómez, Matthew Applegate, Dmitry Rozenberg, W. Darlene Reid, and Darren Roblyer
Biomed. Opt. Express 12(7) 4147-4162 (2021)

Cross-section and feasibility study on the non-invasive evaluation of muscle hemodynamic responses in Duchenne muscular dystrophy by using a near-infrared diffuse optical technique

Wen-Chin Weng, Jung-Chih Chen, Chia-Yen Lee, Chia-Wei Lin, Wang-Tso Lee, Jeng-Yi Shieh, Chia-Chen Wang, and Ching-Cheng Chuang
Biomed. Opt. Express 9(10) 4767-4780 (2018)

Nondestructive quantification of the soluble-solids content and the available acidity of apples by Fourier-transform near-infrared spectroscopy

Yibin Ying, Yande Liu, and Yang Tao
Appl. Opt. 44(25) 5224-5229 (2005)

Nondestructive determination of SSC in an apple by using a portable near-infrared spectroscopy system

Yizhe Zhang, Jipeng Huang, Qiulei Zhang, Jinwei Liu, Yanli Meng, and Yan Yu
Appl. Opt. 61(12) 3419-3428 (2022)

Detailing renal hemodynamics and oxygenation in rats by a combined near-infrared spectroscopy and invasive probe approach

Dirk Grosenick, Kathleen Cantow, Karen Arakelyan, Heidrun Wabnitz, Bert Flemming, Angela Skalweit, Mechthild Ladwig, Rainer Macdonald, Thoralf Niendorf, and Erdmann Seeliger
Biomed. Opt. Express 6(2) 309-323 (2015)