Abstract

Most super-resolution microscopy thus far has exploited the photophysics of fluorescent molecules. And, though several techniques for super-resolution fluorescence microscopy have found wide use in routine imaging of cells, no approaches have emerged that demonstrate super-resolution imaging in scattering tissues. Recently, we introduced a super-resolution-imaging method, multiphoton spatial-frequency-modulated imaging (MP-SPIFI), that provides enhanced resolution for both luminescent and coherent nonlinear interactions, and that opens a path for super-resolution imaging deep inside of scattering tissues.

© 2016 Optical Society of America