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Resolving Single Molecules in Flow Cytometer in Presence of Fluorescent Bursts via an Optical Quantum Measurement

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Abstract

We prove high signal-to-noise (SNR>6) in single-biomarker detection with a quantum-enabled flow cytometer. We observe the nonclassical signal from single biomarkers and differentiate it from the spurious detection of “bright” classical particles based on experimentally characterized statistical properties and quantum measurement.

© 2023 The Author(s)

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