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Conferences > ECBO > 2023 > PS12627 > 126272G
  • Translational Biophotonics: Diagnostics and Therapeutics III
  • Technical Digest Series (Optica Publishing Group, 2023),
  • paper 126272G
  • •https://doi.org/10.1117/12.2670922

Differentiation of collagen-related skin diseases through polarimetry and fluorescence

Tsanislava I. Genova, Deyan D. Ivanov, Lidia B. Zaharieva, Victoria S. Mircheva, Tatiana Novikova, Razvigor Ossikovski, and Petranka P. Troyanova

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Abstract

Diagnosis of degenerative collagen-related skin diseases is a complex process that requires histopathological evaluation of various pathological alterations, which in addition are not unambiguous in themselves. Fluorescence spectroscopy has proven to be valuable tool for tissue differentiation, whereas the biomedical application of tissue polarimetry is establishing as a valuable diagnostic modality. In this work we present the evaluation of experimental results of histology tissue slides from three collagen-related skin diseases: psoriasis, lupus and scleroderma, through fluorescence spectroscopy and Muller polarimetry.

© 2023 SPIE

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