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Conferences > ICOL > 1984 > MD > MD7

Fluorescence Depolarization of Fluorescein in Living Lymphocytes

Shuichi Kinoshita, Tatsuya Fukami, Akiya Saito, Kuniko Hirata, Takashi Kushida, Yoshihiro Kinoshita, and Shuhei Kimura

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Abstract

The degree of polarization of fluorescence from fluorescein, introduced into living lymphocytes, changes according to physiological conditions of the cells and also with antigenic stimulations on lymphocytes. This property can be used for a sensitive detection of malignant diseases. However, the physical mechanism of this fluorescence depolarization is not yet known.

© 1984 Optical Society of America

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