Unveiling metabolic changes in ex vivo brain tissue through intrinsic NADH autofluorescence imaging using the advanced non-linear optical modality

Gagan Raju; Gireesh Gangadharan; Vishwanath Managuli; KK Mahato; Nirmal Mazumder

doi:10.1364/LS.2023.LD1.8

Frontiers in Optics + Laser Science 2023 (FiO, LS)
Technical Digest Series (Optica Publishing Group, 2023),
paper LD1.8
•https://doi.org/10.1364/LS.2023.LD1.8

Unveiling metabolic changes in ex vivo brain tissue through intrinsic NADH autofluorescence imaging using the advanced non-linear optical modality

Gagan Raju, Gireesh Gangadharan, Vishwanath Managuli, KK Mahato, and Nirmal Mazumder

Laser Science 2023

Tacoma, Washington United States
9–12 October 2023
ISBN: 978-1-957171-29-6

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G. Raju, G. Gangadharan, V. Managuli, K. Mahato, and N. Mazumder, "Unveiling metabolic changes in ex vivo brain tissue through intrinsic NADH autofluorescence imaging using the advanced non-linear optical modality," in Frontiers in Optics + Laser Science 2023 (FiO, LS), Technical Digest Series (Optica Publishing Group, 2023), paper LD1.8.

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Abstract

Study explores the application of two photon fluorescence lifetime imaging modality to reveal metabolic alterations in ex vivo brain tissue by analyzing intrinsic NADH autofluorescence, providing valuable insights into brain metabolism and potential disease mechanisms.

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